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The Sequential Organ Failure Assessment (SOFA) score is used to assess organ dysfunction and predict mortality in intensive care patients.
PaO₂
Normal 80-100mmHg
 
FiO₂
 
Platelets
Normal 150 - 400 x10³/µL
 
Bilirubin
Normal <1 mg/dL
 
Hypotension
 
Glasgow Coma Scale
 
Creatinine
Normal 50 - 120 µmol/L
 
Urine Output
 
Calculate
 
 

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0 1 2 3 4
Respiratory
PaO₂ : FiO₂ ratio
(mmHg)		 >400 ≤400 ≤300 ≤200 ≤100
Coagulation
Platelets
(x10³/µL)		 >150 ≤150 ≤100 ≤50 ≤20
Liver
Bilirubin
 <1.2 1.2 - 1.9 2 - 5.9 6 - 12 >12
Cardiovascular
Hypotension		 No hypotension MAP <70mmHg Dop ≤5 or any dub Dop >5,
adr ≤0.1,
norad ≤0.1		 Dop >15,
adr >0.1,
norad >0.1
CNS
Glasgow Coma Scale		 15 13 - 14 10 - 12 6 - 9 3 - 6
Renal
Creatinine (µmol/L)
Urine output (mL/day)		 Cr <106 Cr 106 - 176 Cr 177 - 308 Cr 309 - 441
UO <500		 Cr ≥442
UO <500
0 1 2 3 4
Resp
PF ratio
(mmHg)		 >400 ≤400 ≤300 ≤200 ≤100
Coag
Platelets
(x10³/µL)		 >150 ≤150 ≤100 ≤50 ≤20
Liver
Bilirubin
 <1.2 1.2 - 1.9 2 - 5.9 6 - 12 >12
Cardio
BP		 Normal BP MAP <70mmHg Dop ≤5 or any dub Dop >5,
adr ≤0.1,
norad ≤0.1		 Dop >15,
adr >0.1,
norad >0.1
CNS
Glasgow Coma Scale		 15 13 - 14 10 - 12 6 - 9 3 - 6
Renal
Creatinine (µmol/L)
Urine output (mL/day)		 Cr <106 Cr 106 - 176 Cr 177 - 308 Cr 309 - 441
UO <500		 Cr ≥442
UO <500

MAP: mean arterial pressure, dop: dopamine, dob: dobutamine, adr: adrenaline, norad: noradrenaline
 Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, Reinhart CK, Suter P, Thijs LG. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive care medicine. 1996 Jul 1;22(7):707-10.
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