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The MASCC Risk Index is used to assess for risk of serious complications of febrile neutropaenia in patients with cancer. Low risk patients (≥21 points) may be safe for outpatient management, while high risk patients (<21 points) should be admitted and monitored closely.

Serious complications may include hypotension, respiratory failure, ICU admission, DIC, confusion, congestive cardiac failure, severe bleeding, arrhythmia or renal failure.
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