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The 4Ts Score for HITS

The 4Ts score is a means of stratifying risk of heparin-induced thrombocytopaenia syndrome (HITS), based on the onset and severity of thrombocytopaenia following heparin administration, as well as presence of features of HITS.

Thrombocytopaenia
 
 
 
Timing of Platelet Count Fall
 
 
 
Thrombosis / Other Sequelae
 
 
 
Other Causes of Thrombocytopaenia
 
 
 
Calculate
 
 

 
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  • Low probability (1-3) - HITS unlikely; negative predictive value 99.8%
  • Moderate probability (4-5) - risk of HITS ~13%
  • High probability (6-8) - positive predictive value 64%
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