Serum-Ascites Albumin Gradient | Ascitic Fluid - MedSchool
Sign up to start your free trial of MedSchool Premium!Get Started
 
Ascitic Fluid
 
 
 

Serum-Ascites Albumin Gradient

 
 
Bookmark

Overview

  • The serum-ascites albumin gradient (SAAG) is used to differentiate between portal hypertension and other causes of ascites.
    • Formula

    • SAAG = [serum albumin] - [ascitic albumin]

Elevated Serum-Ascites Albumin Gradient

  • Elevated SAAG (≥1.1 g/dL) is indicative of portal hypertension.
    • Causes of Ascites with Elevated SAAG

    • Cirrhosis
    • Cardiac ascites
    • Alcoholic hepatitis
    • Massive liver metastasis
    • Fulminant hepatic failure
    • Portal venous thrombosis

Reduced Serum-Ascites Albumin Gradient

  • Ascites with a low SAAG (<1.1 g/dL) is suggestive of a non-portal hypertension cause of ascites.
    • Causes of Ascites with Reduced SAAG

    • Infection - bacterial peritonitis, pancreatitis, TB
    • Malignancy
    • Nephrotic syndrome
Last updated on November 29th, 2017
 
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
 
Feedback