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Cranial Nerves
Cranial Nerves

Internuclear Ophthalmoplegia

February 15th, 2021


If present, internuclear ophthalmoplegia is highly suggestive of a lesion affecting the medial longitudinal fasciculus within the brainstem, which is involved in conjugate gaze.
The most common causes of lesions in this area would be stroke (older patients) or multiple sclerosis (younger patients).
  • Look For

  • Inability to adduct one eye, with nystagmus in the other eye.
  • Causes of Internuclear Ophthalmoplegia

  • Multiple sclerosis
  • Ischaemic stroke
  • Trauma
  • Infection
  • Tumour
  • Haemorrhage
  • Vasculitis
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