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Urine Leukocyte Esterase

March 4th, 2023
 
 
 
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Overview

Leukocyte esterase (LE) is an enzyme produced by white blood cells. If leukocyte esterase is present in urine then this is indicative of an increase in leukocytes in urine, also known as pyuria. 
  • Causes of Pyuria

  • Infection - urethritis, prostatitis, cystitis, pyelonephritis, tuberculosis
  • Neoplasm - renal, bladder, protate
  • Inflammation - interstitial nephritis, interstitial cystitis, Kawasaki disease, SLE
  • Foreign body - renal calculus, indwelling catheter, ureteric stents
  • Polycystic kidney disease
  • Pelvic irradiation
  • Pregnancy
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