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Thyroid Function




  • Thyroglobulin (Tg) is a storage form of the thyroid hormones produced by follicular cells of the thyroid, and is released into serum in conjunction with T3 and T4.
  • Thyroglobulin (Tg) is not routinely measured in clinical practice.
    • Clinical Use of Thyroglobulin Testing

    • Diagnosis of thyrotoxicosis factitia - used to distinguish surreptitious thyroxine ingestion from other causes of hyperthyroidism, as thyroglobulin will remain normal with exogenous thyroxine use
    • Thyroid cancer - assessing for residual tumour post resection, or monitoring for recurrence
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