Thyroid Function

Primary Hypothyroidism



  • Primary hypothyroidism originates from pathology affecting thyroid tissue, resulting in reduced production of thyroid hormones.
    • Look For

    • Elevated TSH with reduced T4.
    • Causes of Primary Hypothyroidism

    • Autoimmune thyroiditis - Hashimoto’s, atrophic
    • Hypothyroid phase of thyroiditis
    • Iatrogenic - radioiodine therapy, thyroidectomy, external irradiation of the neck
    • Drugs - amiodarone, lithium, interferons, interleukin-2, iodide
    • Iodine deficiency
    • Thyroid infiltration - amyloidosis, tumour
    • Congenital hypothyroidism
Last updated on July 29th, 2019
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