Low / Normal TSH with Low T4 | Thyroid Function - MedSchool
Sign up to start your free trial of MedSchool Premium!Get Started
 
Thyroid Function
 
 
Thyroid Function
 
 
Bookmark
A reduced or normal TSH with a reduced T4 level is classically suggestive of a central cause of hypothyroidism (i.e. reduced hypothalamic or pituitary release of TRH or TSH respectively). However, central hypothyroidism is rare and perhaps a more common cause is the non-thyroidal illness (sick euthyroid) syndrome.
 

Low / Normal TSH with Low T4

 
 
Bookmark

Overview

  • A reduced or normal TSH with a reduced T4 level is classically suggestive of a central cause of hypothyroidism (i.e. reduced hypothalamic or pituitary release of TRH or TSH respectively). However, central hypothyroidism is rare and perhaps a more common cause is the non-thyroidal illness (sick euthyroid) syndrome.
    • Causes of Reduced / Normal TSH with Reduced T4

    • Nonthyroidal illness
    • Recent treatment of hyperthyroidism
    • Central hypothyroidism
    • Congenital TSH or TRH deficiency
    • Assay interference
Last updated on July 29th, 2019
 
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
 
Feedback