Thyroid Function
 

Free Triiodothyronine (T3)

 
 
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Overview

  • Free T3 is a measure of the triiodothyronine not bound to serum proteins such as thyroid-binding globulin, albumin or transthyretin.
      • Normal Range

      • 2.0 - 3.5 pg/mL
  • Measurement of free T3 is not generally required for the diagnosis of thyroid disease.
    • Pearls

    • Free T3 measurement is useful for diagnosing T3 thyrotoxicosis in patients with reduced TSH and normal T4.
    • Free T3 may be useful to confirm suspected hyperthyroidism, as it becomes elevated prior to T4.
    • Free T3 is not useful in the diagnosis of hypothyroidism as it is the last test to become abnormal in this setting.
 
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