Bronchial Challenge | Lung Function Tests - MedSchool
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Lung Function Tests

Bronchial Challenge



    • Procedure

    • Histamine or methacholine is given to stimulate bronchoconstriction
    • FEV₁ is measured before and after the dose.
    • Significance

    • Worsening FEV₁ after the stimulus is suggestive of asthma.
  • The test has high negative predictive value, though the positive predictive value is poor as certain other respiratory conditions will result in false positive.
Last updated on November 15th, 2017