The Myeloma Screen Bookmark ShareMultiple myeloma may present with typical features such as hypercalcaemia, renal dysfunction, anaemia and bony lesions. This section outlines the tests used to screen for multiple myeloma.On this page: The Myeloma ScreenOther Tests for Suspected Myeloma***Manifestations of MyelomaThe Myeloma ScreenSerum ImmunoglobulinsIgG, IgA, IgMSerum Free Light ChainsAbnormal ratio is suggestive of monoclonal gammopathySerum Protein ElectrophoresisAlbumin, alpha, beta and gamma bandsSerum Immunofixation ElectrophoresisType of Ig, type of light chain, paraprotein levelOther Tests for Suspected MyelomaSerum CalciumHypercalcaemiaCreatinineEvidence of renal failureFBC and Blood FilmNormocytic, normochromic anaemia with rouleuxSkeletal SurveyX-ray or CTTo assess for lytic lesions