MedSchool: Ace Your OSCEsThe Medical Company
GET - On the App Store
Liver Function Tests
Liver Function Tests


February 15th, 2021


A copper-containing protein produced by the liver that binds ~90% of plasma copper.
Caeruloplasmin is an acute phase reactant.
  • Significance

  • Used as a test for Wilson's disease, in conjunction with serum copper concentration.

Reduced Caeruloplaemin

  • Causes of Reduced Caeruloplasmin

  • Wilson's disease
  • Reduced synthesis - liver disease, malnutrition, malabsorption, TPN
  • Increased loss - nephrotic syndrome, protein-losing enteropathy, Menke's disease

Elevated Caeruloplasmin

  • Causes of Elevated Caeruloplasmin

  • Acute phase reaction - infection, inflammation, malignancy
  • Endocrine - pregnancy, hormone replacement
Next Page
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now

Snapshot: Initialising...