MedSchool: Ace Your OSCEsThe Medical Company
GET - On the App Store
Liver Function Tests
Liver Function Tests




  • Albumin is a group of serum proteins produced by the liver that maintain oncotic pressure and transport certain hydrophobic compounds.
      • Normal Range

      • 32 - 45 g/L
  • Albumin has a plasma half-life of three weeks, meaning that its concentration changes very slowly in response to changes in synthesis.


  • A reduction in serum albumin may occur due to reduced production, increased proteolysis (protein breakdown) or increased loss.
  • As albumin is essential for the maintenance of oncotic pressure, hypoalbuminaemia may manifest with widespread oedema.
    • Causes of Hypoalbuminaemia

    • Reduced synthesis - malnutrition, malabsorption, liver disease
    • Increased breakdown - infection, inflammation, malignancy, hyperthyroidism
    • Increased loss - nephrotic syndrome, protein-losing enteropathy, severe burns
    • Dilutional


  • Increased serum albumin is uncommon, and strongly suggests dehydration.
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now