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Liver Function Tests

 
 
 
Liver Function
Markers of Cirrhosis
Viral Hepatitis Screen
Other Tests
 
 

Albumin

 
 
  • Albumin is a group of serum proteins produced by the liver that maintain oncotic pressure and transport certain hydrophobic compounds.
      • Normal Range
      • 32 - 45 g/L
  • Albumin has a plasma half-life of three weeks, meaning that its concentration changes very slowly in response to changes in synthesis.

Hypoalbuminaemia

  • Reduced serum albumin.
    • Causes of Hypoalbuminaemia
    • Reduced synthesis - malnutrition, malabsorption, liver disease
    • Increased breakdown - infection, inflammation, malignancy, hyperthyroidism
    • Increased loss - nephrotic syndrome, protein-losing enteropathy, severe burns
    • Dilutional

Hyperalbuminaemia

  • Increased serum albumin.
    • Significance
    • Indicative of dehydration.
 
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