Login or Register to unlock everything MedSchool has to offer!
 
 
Liver Function Tests
 
 
Liver Function Tests
Liver function tests are used to assess for evidence of acute or chronic liver disease. Patterns of derangement include hepatocellular dysfunction, cholestatic change and changes of cirrhosis. 
 

Albumin

 
 

Overview

  • Albumin is a group of serum proteins produced by the liver that maintain oncotic pressure and transport certain hydrophobic compounds.
      • Normal Range

      • 32 - 45 g/L
  • Albumin has a plasma half-life of three weeks, meaning that its concentration changes very slowly in response to changes in synthesis.

Hypoalbuminaemia

  • Reduced serum albumin.
    • Causes of Hypoalbuminaemia

    • Reduced synthesis - malnutrition, malabsorption, liver disease
    • Increased breakdown - infection, inflammation, malignancy, hyperthyroidism
    • Increased loss - nephrotic syndrome, protein-losing enteropathy, severe burns
    • Dilutional

Hyperalbuminaemia

  • Increased serum albumin.
    • Significance

    • Indicative of dehydration.
Last updated on November 25th, 2019
 
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------

Associated Diseases
BETA

Endocrinology
Gastrointestinal
Nutrition & Metabolic
Oncology
Malignant Neoplasms
Renal & Urinary
Trauma
 
Feedback