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February 15th, 2021
On this page:Eosinophilia


Eosinophils are granulocytes with a bilobed nucleus, blue cytoplasm and orange-red cytoplasmic granules
    • Normal Range

    • 0.0 - 0.5 x 10⁹/L
    • 1 - 4% of total leukocytes


Eosinophilia refers to an increase in circulating eosinophils.
  • Causes of Eosinophilia

  • Allergy - asthma, allergic rhinitis, chronic sinusitis, atopic dermatitis, eosinophilic oesophagitis, allergic bronchopulmonary aspergillosis (ABPA), chronic eosinophilic pneumonia
  • Drug hypersensitivity - e.g. penicillins, cephalosporins, sulpha drugs
  • Parasites - helminths (especially Strongyloides), protozoa
  • Autoimmune - eosinophilic granulomatosis with polyangiitis (Churg-Strauss), other autoimmune diseases (rarely)
  • Malignancy - chronic eosinophilic leukaemia, lymphoma, certain solid organ malignancies
  • Primary eosinophilia
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