Eosinophils | Full Blood Count - MedSchool
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Full Blood Count
 
 
Full Blood Count
Eosinophils are granulocytes with a bilobed nucleus, blue cytoplasm and orange-red cytoplasmic granules
 

Eosinophils

 
 

Overview

  • Eosinophils are granulocytes with a bilobed nucleus, blue cytoplasm and orange-red cytoplasmic granules
      • Normal Range

      • 0.0 - 0.5 x 10‎⁹/L
      • 1 - 4% of total leukocytes

Eosinophilia

  • Increased circulating eosinophils.
    • Causes of Eosinophilia

    • Allergy - asthma, allergic rhinitis, chronic sinusitis, atopic dermatitis, drug allergy, eosinophilic oesophagitis, allergic bronchopulmonary aspergillosis (ABPA), chronic eosinophilic pneumonia
    • Parasites - helminths (especially Strongyloides), protozoa
    • Autoimmune - eosinophilic granulomatosis with polyangiitis (Churg-Strauss), other autoimmune diseases (rarely)
    • Malignancy - acute or chronic eosinophilic leukaemia, lymphoma, certain solid organ malignancies
    • Primary eosinophilia

Eosinopaenia

  • Reduced circulating eosinophils.
    • Significance

    • Seen with prolonged steroid administration.
Last updated on March 24th, 2020
 
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