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Tachy-Brady Syndrome

February 15th, 2021


Tachycardia-bradycardia syndrome is a manifestation of sinus node dysfunction where bradycardia is interspersed with periods of supraventricular tachycardia.
  • Look For

  • Alternating episodes of bradycardia and supraventricular tachycardia (AF, flutter, atrial tachycardia or AVNRT).
  • Causes of Tachy-Brady Syndrome

  • Intrinsic

  • Idiopathic degeneration
  • Myocardial infarction
  • Infiltrative disease - sarcoidosis, amyloidosis, haemochromatosis
  • Connective tissue disease - SLE, scleroderma, RA
  • Cardiac surgery - valvular surgery, correction of congenital heart disease
  • Infections - Lyme disease, endocarditis
  • Extrinsic

  • Physiologic - sleep, athletes
  • Autonomic - neurocardiogenic syncope, carotid sinus hypersensitivity
  • Drugs - beta blockers, calcium channel blockers, digoxin, adenosine, ivabradine, clonidine, acetylcholinesterase inhibitors
  • Hypothyroidism
  • Hypothermia
  • Hyperkalaemia
  • Obstructive sleep apnoea
  • Raised intracranial pressure
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