CSF Interpretation
September 13th, 2020
Overview
Analysis of cerebrospinal fluid is used to identify infections affecting the central nervous system. CSF testing (particularly of proteins) also be used in the diagnosis of demyelinating diseases such as Guillain-Barre syndrome and multiple sclerosis.
| Normal | Viral | Bacterial | Fungal / TB | |
| Opening Pressure | 5-20 cmH2O | Normal / Elevated | Elevated | Elevated |
| Appearance | Clear | Clear | Turbid | Clear / Turbid / Opaque |
| WBC | <5 No PMNs | 10-1000 | >100 >80% PMNs | 50-500 |
| RBC | <10 | <10 | <10 | <10 |
| Protein | 15-45 mg/dL | Elevated | Elevated | Elevated |
| Glucose | >60% serum | >60% serum | <40% serum | <40% serum |
| Other | PCR for HSV/VZV | Gram stain & culture | Fungal culture, AFB |
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