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Chest X-Ray

Interstitial Lung Disease

February 15th, 2021


The chest x-ray has low sensitivity and specificity for the diagnosis of interstitial lung disease, and a high resolution CT is the imaging modality of choice.
Interstitial lung disease may be suggested by reticular or reticulonodular opacities on chest x-ray.
  • Example

  • Increased interstitial markings with peripheral and basal predominance
  • Increased interstitial markings with peripheral and basal predominance
  • Causes of Interstitial Lung Disease

  • ILD of Known Association

  • Connective tissue disease - rheumatoid arthritis, scleroderma, systemic lupus erythematosus, Sjogren's syndrome, polymyositis / dermatomyositis
  • Medications - methotrexate, nitrofurantoin, bleomycin
  • Occupational exposure - silicosis, asbestosis
  • Granulomatous ILD

  • Sarcoidosis
  • Hypersensitivity pneumonitis
  • Idiopathic Interstitial Pneumonias

  • Idiopathic pulmonary fibrosis
  • Others - idiopathic non-specific interstitial pneumonia, acute interstitial pneumonia, cryptogenic organising pneumonia, lymphocytic interstitial pneumonia, desquamative interstitial pneumonia
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