The Blood Film
Examination of peripheral blood under a microscope can provide a significant amount of information regarding the morphology of red blood cells, white blood cells and platelets.
Size
Microcytosis, macrocytosis
Colour
Hypochromia, hyperchromia, polychromasia
Shape
Poikilocytosis
Inclusion Bodies
Howell Jolly bodies, basophilic stippling, Pappenheimer bodies, Cabot ring
Nucleated Red Blood Cells
Aggregation
Rouleaux formation
Findings on Supravital Staining
Heinz bodies, haemoglobin H inclusions
Smudge cells
Cellular remnants
Leukoerythroblastic Blood Film
Left shift of granulocytes with nucleated red blood cells
Changes of Hyposplenism
Target cells, Howell Jolly bodies, Pappenheimer bodies, lymphocytosis, monocytosis, thrombocytosis
Megaloblastic Changes
Macroovalocytes, neutrophil hypersegmentation
Myelodysplastic Changes
Anisopoikilocytosis, round macrocytes, hypolobated / hypogranular neutrophils, platelet anisocytosis