Overview
Basophils are granulocytes with large bluish (basophilic) granules. These uncommon cells play a role in the pathogenesis of allergy.
Basophilia
Basophilia refers to an increase in the number of circulating basophils.
Causes of Basophilia
- Viral infection
- Allergies - asthma, atopic dermatitis, allergic rhinitis
- Inflammation - autoimmune disease, graft vs host disease
- Myeloproliferative neoplasms - CML, polycythaemia vera, myelofibrosis
- Hodgkin lymphoma
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