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Autoimmune Screen

Antistreptolysin (ASO) Titre

September 12th, 2020


The antistreptolysin (ASO titre) measures the presence and amount of antibody directed against streptolysin O, a streptococcal exotoxin.
    • Normal Range

    • <200 U/mL
Elevation of the ASO titre is indicative of recent group A streptococcal infection, which may suggest the presence of poststreptococcal glomerulonephritis or acute rheumatic fever in patients with concerning clinical features.
  • Causes of Elevated Antistreptolysin Titre

  • Group A streptococcal infection - pharyngitis, tonsillitis, scarlet fever, impetigo, cellulitis, necrotising fasciitis, septic arthritis, osteomyelitis
  • Poststreptococcal glomerulonephritis
  • Acute rheumatic fever
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