Haptoglobin
September 12th, 2020
Overview
Haptoglobin is an alpha-2 glycoprotein secreted mainly by the liver that binds plasma free haemoglobin following red cell lysis, and as such is reduced in the presence of haemolysis (particularly intravascular haemolysis).
Normal Range
- 36 - 195 mg/dL
Haptoglobin is an acute phase reactant, and as such will be increased in the presence of infection, inflammation or malignancy.
Causes of Increased Haptoglobin
- Infection
- Inflammation
- Malignancy
- Trauma (including surgery)
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