Toxic Granulation of Neutrophils
March 30th, 2020
Overview
Toxic granulation is present when there is an increase in the number of large basophilic granules within circulating neutrophils.
Levels of toxic granulation are highly correlated with C-reactive protein (CRP) values in patients with infection or inflammation.
Causes of Toxic Granulation
- Bacterial infection
- Inflammation
- G-CSF
- Pregnancy
- Recovery post bone marrow suppression
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