Test Findings
 

Thrombocytosis

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Overview

  • Thrombosis refers to an increase in circulating platelets. This may occur due to a myeloproliferative neoplasm, a reactive increase in platelet production, or a shift in platelets from the spleen into the circulation.
    • Causes of Thrombocytosis

    • Primary

    • Myeloproliferative neoplasms - essential thrombocythaemia, polycythaemia vera, chronic myeloid leukaemia, myelofibrosis
    • Increased Production

    • Infection
    • Inflammation - autoimmune disease, major surgery, trauma, fracture, burns, pancreatitis, infarction
    • Malignancy
    • Drugs - adrenaline, corticosteroids, vinca alkaloids, thrombopoietin
    • Acute haemorrhage
    • Iron deficiency
    • Platelet Shift

    • Hyposplenism - splenectomy, liver cirrhosis, coeliac disease, sickle cell disease, SLE
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