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Test Findings
 
 

Reduced Red Cell Count

 
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Overview

  • Reduced circulating red blood cells.
    • Causes of Reduced Red Cell Count

    • Reduced RBC Production

    • Haematinic deficiency - B12, folate, iron
    • Bone marrow pathology - aplastic anaemia, myeloproliferative diseases, myelofibrosis
    • Endocrine - EPO deficiency, hypothyroidism
    • Anaemia of chronic disease (infection / inflammation / malignancy)
    • Sideroblastic anaemia
    • Thalassaemias
    • Increased RBC Destruction (Haemolysis)

    • Immune haemolysis - autoimmune, alloimmune, drug-induced
    • Red cell fragmentation - thrombotic microangiopathies, mechanical haemolysis
    • Intrinsic RBC disorders - enzymopathies, membranopathies, haemoglobinopathies
    • Hypersplenism
    • Other - infection, copper, lead, hypophosphataemia
    • RBC Loss

    • Trauma
    • Gastrointestinal bleed
    • Bleeding from another source e.g. urinary tract
    • Factitious

    • Dilutional - excess fluid administration, pregnancy
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