PT/INR Correction with Mixing
Correction of PT/INR with Mixing
- If the PT/INR is initially elevated but becomes normal when control plasma is added, this suggests that there is factor deficiency as the cause of coagulopathy.
- This occurs commonly in the setting of warfarin or vitamin K deficiency, however may occur in the context of deficiencies affecting multiple pathways.
Causes of PT/INR Correction with Mixing
- Warfarin
- Vitamin K deficiency
- Congenital factor deficiency
- Disseminated intravascular intracoagulation
- Liver failure
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