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Test Findings

PT/INR Correction with Mixing


Correction of PT/INR with Mixing

  • If the PT/INR is initially elevated but becomes normal when control plasma is added, this suggests that there is factor deficiency as the cause of coagulopathy.
  • This occurs commonly in the setting of warfarin or vitamin K deficiency, however may occur in the context of deficiencies affecting multiple pathways.
    • Causes of PT/INR Correction with Mixing

    • Warfarin
    • Vitamin K deficiency
    • Congenital factor deficiency
    • Disseminated intravascular intracoagulation
    • Liver failure
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