Prolonged Thrombin Time
April 24th, 2019
Overview
Interpretation
- Prolonged reptilase - fibrinogen defects, fibrin degradation products
- Normal reptilase - heparin, factor IIa inhibitors
Causes of Prolonged Thrombin Time
- Fibrinogen defects - hypofibrinogenaemia, afibrogenaemia, dysfibrinogenaemia
- Fibrin degradation products (e.g. in DIC)
- Factor IIa inhibitors (e.g. dabigatran)
- Heparin
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