Test Findings
 

Prolonged Thrombin Time

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Overview

    • Interpretation

    • Prolonged reptilase - fibrinogen defects, fibrin degradation products
    • Normal reptilase - heparin, factor IIa inhibitors
    • Causes of Prolonged Thrombin Time

    • Fibrinogen defects - hypofibrinogenaemia, afibrogenaemia, dysfibrinogenaemia
    • Fibrin degradation products (e.g. in DIC)
    • Factor IIa inhibitors (e.g. dabigatran)
    • Heparin
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