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Test Findings

Prolonged Thrombin Time

April 24th, 2019


  • Interpretation

  • Prolonged reptilase - fibrinogen defects, fibrin degradation products
  • Normal reptilase - heparin, factor IIa inhibitors
  • Causes of Prolonged Thrombin Time

  • Fibrinogen defects - hypofibrinogenaemia, afibrogenaemia, dysfibrinogenaemia
  • Fibrin degradation products (e.g. in DIC)
  • Factor IIa inhibitors (e.g. dabigatran)
  • Heparin
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Snapshot: Initialising...