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Normocytic Normochromic Anaemia

April 20th, 2020
 
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Overview

  • Look For

  • Reduced serum haemoglobin, haematocrit and red cell count
  • Normal MCV (80 - 100fL)
  • Normal MCH / MCHC
  • Causes of Normocytic Normochromic Anaemia

  • Dilutional - excess fluid administration, pregnancy
  • Acute haemorrhage
  • Chronic kidney disease
  • Anaemia of chronic disease (infection / inflammation / malignancy)
  • Pure red cell aplasia - Diamond-Blackfan syndrome, drugs, lymphoma, CLL, parvovirus B19
  • Bone marrow infiltration - myelofibrosis, bone marrow metastases
  • Early megaloblastic anaemia
  • Early iron deficiency anaemia
  • Haemolytic anaemia
  • Congenital sideroblastic anaemia
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