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Lymphopaenia

April 24th, 2019
 
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Overview

Lymphopaenia refers to a reduction in the number of circulating lymphocytes.
  • Causes of Lymphopaenia

  • Inherited
  • Primary immunodeficiency disorders - e.g. severe combined immunodeficiency, Wiskott-Aldrich syndrome
  • Acquired
  • Acute stress - infection, trauma, burns, surgery
  • Drugs - corticosteroids, cytotoxic chemotherapy, methotrexate, azathioprine, rituximab, clozapine
  • HIV infection / AIDS
  • Autoimmune disease (especially SLE)
  • Cushing's syndrome
  • Hodgkin lymphoma
  • Aplastic anaemia
  • Alcohol abuse
  • Sarcoidosis
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