Lymphopaenia
April 24th, 2019
Overview
Lymphopaenia refers to a reduction in the number of circulating lymphocytes.
Causes of Lymphopaenia
- Inherited
- Primary immunodeficiency disorders - e.g. severe combined immunodeficiency, Wiskott-Aldrich syndrome
- Acquired
- Acute stress - infection, trauma, burns, surgery
- Drugs - corticosteroids, cytotoxic chemotherapy, methotrexate, azathioprine, rituximab, clozapine
- HIV infection / AIDS
- Autoimmune disease (especially SLE)
- Cushing's syndrome
- Hodgkin lymphoma
- Aplastic anaemia
- Alcohol abuse
- Sarcoidosis
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