Hypoalbuminaemia
Overview
A reduction in serum albumin may occur due to reduced production, increased proteolysis (protein breakdown) or increased loss.
As albumin is essential for the maintenance of oncotic pressure, hypoalbuminaemia may manifest with widespread oedema.
Causes of Hypoalbuminaemia
- Reduced synthesis - malnutrition, malabsorption, liver disease
- Increased breakdown - infection, inflammation, malignancy, hyperthyroidism
- Increased loss - nephrotic syndrome, protein-losing enteropathy, severe burns
- Dilutional
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