Hypoalbuminaemia

Overview

• A reduction in serum albumin may occur due to reduced production, increased proteolysis (protein breakdown) or increased loss.
• As albumin is essential for the maintenance of oncotic pressure, hypoalbuminaemia may manifest with widespread oedema.

• • Causes of Hypoalbuminaemia

  • Reduced synthesis - malnutrition, malabsorption, liver disease
  • Increased breakdown - infection, inflammation, malignancy, hyperthyroidism
  • Increased loss - nephrotic syndrome, protein-losing enteropathy, severe burns
  • Dilutional