Hypoalbuminaemia

 
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Overview

  • A reduction in serum albumin may occur due to reduced production, increased proteolysis (protein breakdown) or increased loss.
  • As albumin is essential for the maintenance of oncotic pressure, hypoalbuminaemia may manifest with widespread oedema.

    • Causes of Hypoalbuminaemia

    • Reduced synthesis - malnutrition, malabsorption, liver disease
    • Increased breakdown - infection, inflammation, malignancy, hyperthyroidism
    • Increased loss - nephrotic syndrome, protein-losing enteropathy, severe burns
    • Dilutional
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