Hypoalbuminaemia
Overview
- A reduction in serum albumin may occur due to reduced production, increased proteolysis (protein breakdown) or increased loss.
- As albumin is essential for the maintenance of oncotic pressure, hypoalbuminaemia may manifest with widespread oedema.
Causes of Hypoalbuminaemia
- Reduced synthesis - malnutrition, malabsorption, liver disease
- Increased breakdown - infection, inflammation, malignancy, hyperthyroidism
- Increased loss - nephrotic syndrome, protein-losing enteropathy, severe burns
- Dilutional
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