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Test Findings




  • Hyperchromia refers to an increase in the intensity of red blood cell colour. Hyperchromic cells may be spherocytes, microspherocytes or macrocytes.
    • Hyperchromia
    • Signs of Hyperchromia

    • Reduction in central pallor on blood film
    • Increased red cell haemoglobin (MCH / MCHC)
    • Causes of Hyperchromia

    • Spherocytosis - hereditary spherocytosis, immune haemolysis, Clostridium
    • Microspherocytosis - microangiopathic haemolytic anaemia, severe burns
    • Macrocytosis - B12/folate deficiency chronic liver disease, alcohol abuse, hypothyroidism, post splenectomy, aplastic anaemia, myelodysplastic syndrome
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