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Eosinophilia

March 24th, 2020
 
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Overview

Eosinophilia refers to an increase in circulating eosinophils.
  • Causes of Eosinophilia

  • Allergy - asthma, allergic rhinitis, chronic sinusitis, atopic dermatitis, eosinophilic oesophagitis, allergic bronchopulmonary aspergillosis (ABPA), chronic eosinophilic pneumonia
  • Drug hypersensitivity - e.g. penicillins, cephalosporins, sulpha drugs
  • Parasites - helminths (especially Strongyloides), protozoa
  • Autoimmune - eosinophilic granulomatosis with polyangiitis (Churg-Strauss), other autoimmune diseases (rarely)
  • Malignancy - chronic eosinophilic leukaemia, lymphoma, certain solid organ malignancies
  • Primary eosinophilia
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