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Test Findings

Elevated Urea:Creatinine Ratio

April 24th, 2019


A urea:creatinine ratio >100:1 is commonly used as a marker of prerenal renal failure. Any cause of isolated urea elevation may also elevate the ratio.
  • Causes of Elevated Urea:Creatinine Ratio

  • Prerenal renal failure - hypovolaemia, sepsis, renal venoconstriction
  • Dehydration
  • Protein load - GI bleed (especially upper GI), high protein diet
  • Catabolic state - trauma, sepsis, starvation, corticosteroids
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