Elevated Urea:Creatinine Ratio
April 24th, 2019
Overview
A urea:creatinine ratio >100:1 is commonly used as a marker of prerenal renal failure. Any cause of isolated urea elevation may also elevate the ratio.
Causes of Elevated Urea:Creatinine Ratio
- Prerenal renal failure - hypovolaemia, sepsis, renal venoconstriction
- Dehydration
- Protein load - GI bleed (especially upper GI), high protein diet
- Catabolic state - trauma, sepsis, starvation, corticosteroids
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