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Test Findings

Elevated Red Cell Count



  • Increased circulating red blood cells.
    • Causes of Erythrocytosis

    • Primary

    • Primary familial erythrocytosis (EPO receptor mutation)
    • Polycythaemia vera (JAK2 mutation)
    • Secondary

    • Chronic hypoxia - smoking, chronic lung disease, obstructive sleep apnoea, high altitude
    • Renal hypoxia - renal artery stenosis, polycystic kidney disease, post renal transplant
    • Drugs - testosterone, anabolic steroids, erythropoietin
    • Paraneoplastic syndrome (EPO-producing tumour)
    • Congenital - haemoglobinopathies, other mutations
    • Idiopathic
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