×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Test Findings
 
 

Elevated LDH

 
Bookmark

Overview

  • LDH is elevated in haemolysis, and markedly in intravascular haemolysis.
  • As LDH is present in all tissues, its elevation is a nonspecific marker of cell damage. Elevation of specific LDH isoenzymes may point toward a specific pathology, as below.
    • Causes of Elevated Lactate Dehydrogenase

    • Factitious (haemolysed sample)
    • Heart - myocardial infarction, heart failure
    • Brain - ischaemic stroke, traumatic brain injury
    • Kidneys - nephritis, nephrotic syndrome, acute tubular necrosis, infarction
    • Anaemia - haemolytic or megaloblastic
    • Malignancy (especially haematological)
    • Lungs - pulmonary embolism, infarction, obstructive disease, interstitial lung disease, pneumonia
    • Spleen - infarction
    • Pancreas - pancreatitis
    • Liver - hepatitis, infarction, cirrhosis, malignancy, trauma
    • Skeletal muscle - strenuous exercise, rhabdomyolysis, myositis
    • Shock
    • Trauma
    • Hypoxia
    ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
    Want more info like this?
    • Your electronic clinical medicine handbook
    • Guides to help pass your exams
    • Tools every medical student needs
    • Quick diagrams to have the answers, fast
    • Quizzes to test your knowledge
    Sign Up Now