Test Findings
 

Elevated Free T4

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Overview

  • Elevated T4 with suppressed TSH is suggestive of primary hyperthyroidism, while a normal or elevated TSH may be present with certain conditions or due to false elevation.
    • Causes of Elevated Free T4

    • Reduced TSH

    • Primary hyperthyroidism
    • Normal / Elevated TSH

    • TSH secreting pituitary tumour
    • Thyroid hormone resistance
    • Acute psychiatric illness
    • Amiodarone
    • False Elevation

    • Reduced TBG - androgens, glucocorticoids
    • Familial dysalbuminaemic hyperthyroxinaemia
    • Heterophile antibodies
    • Heparin
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