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Test Findings
 
 

Elevated CRP

 
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Overview

C-reactive protein is an acute phase protein that is involved in innate immunity, and is responsible for activating the complement pathway.
    • Normal Range

    • <5 mg/L
  • Causes of Elevated CRP

  • Infection - especially bacterial
  • Inflammatory disease - e.g. polymyalgia rheumatica, IBD, vasculitis, rheumatoid arthritis, seronegative arthritides
  • Tissue necrosis - e.g. myocardial infarction, pancreatic necrosis
  • Pearls

  • Elevated CRP is indicative of an active inflammatory state.
  • Serum CRP rises rapidly, with a maximal concentration reached within two days; it falls quickly once inflammation has resolved.
  • CRP has little efficacy as a screening tool for inflammation.
  • The trend in CRP is useful for monitoring resolution or progression of an inflammatory process.
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    Snapshot: Initialising...