MedSchool: Ace Your OSCEsThe Medical Company
GET - On the App Store
Test Findings

Elevated Creatinine

April 24th, 2019


Elevated serum creatinine is most commonly used as a marker of renal injury, though it is important to remember other causes. Patients who have recently eaten meat or who are undergoing muscle breakdown may have an elevated creatinine that gives a false indication of their true renal function. Certain medications (particularly trimethoprim) can elevate the creatinine without causing renal failure.
  • Causes of Elevated Creatinine

  • Renal Failure

  • Acute kidney injury
  • Chronic kidney disease
  • Other Causes

  • Creatinine intake - cooked meat
  • Muscle breakdown - body building, rhabdomyolysis
  • Reduced creatinine secretion - trimethoprim, ranitidine
  • Assay interference - ketosis, hyperbilirubinaemia, cefoxitin
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now

Snapshot: Initialising...