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Kayser-Fleischer Rings



    • Look For

    • Brown / yellow / gold rings at the margin of the cornea and sclera, encircling the outer iris.
    • Significance

    • An indicator of Wilson's disease, a recessive disorder of copper metabolism resulting in excessive copper deposition.
    • Manifestations of Wilson's Disease

    • Hepatic - chronic liver disease, cirrhosis
    • Corneal - Kayser-Fleischer Rings
    • Basal ganglia - Parkinsonism
    • Renal - renal failure
    • Red blood cells - haemolytic anaemia
    • Psychiatric - severe depression
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