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Distal Weakness



  • Distal weakness is more commonly a manifestation of neuropathy, though may also occur in certain muscular conditions.
    • Signs of Distal Weakness

    • Wasting of the small muscles of the hand
    • Foot drop
    • Distal weakness - particularly affecting the hands, wrists and ankles
    • Distal functional impairment - difficulty opening jars, turning a key, buttoning a shirt
    • Causes of Distal Weakness

    • Unilateral

    • Radiculopathy (C8/T1)
    • Brachial plexopathy
    • Peripheral nerve lesion
    • Bilateral

    • Guillain-Barre syndrome
    • Chronic inflammatory demyelinating polyneuropathy
    • Multifocal motor neuropathy with conduction block
    • Motor neurone disease
    • Inclusion body myositis
    • Myotonic dystrophy
    • Congenital distal myopathies
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