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Chorea

 
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Overview

  • Look For

  • Spontaneous, abrupt, irregular movements. May manifest in the face, neck, torso, arms or legs.
  • Causes of Chorea

  • Inherited disorders - Huntington’s disease, Friedrich’s ataxia, ataxia-telangiectasia, tuberous sclerosis, benign hereditary chorea, mitochondrial disease
  • Vascular - ischaemic / haemorrhagic stroke
  • CNS tumour
  • Drugs - levodopa, antiepileptics, antipsychotics, stimulants, benzodiazepines, OCP, lithium
  • Infectious - Sydenham’s chorea (rheumatic fever), herpes simplex encephalitis, HIV, prions
  • Metabolic - pregnancy, thyrotoxicosis
  • Autoimmune - SLE, anti-phospholipid syndrome, scleroderma
The term chorea derives from the Greek koreia, ‘dance'.
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