Signs
 

Chorea

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Overview

    • Look For

    • Spontaneous, abrupt, irregular movements. May manifest in the face, neck, torso, arms or legs.
    • Causes of Chorea

    • Inherited disorders - Huntington’s disease, Friedrich’s ataxia, ataxia-telangiectasia, tuberous sclerosis, benign hereditary chorea, mitochondrial disease
    • Vascular - ischaemic / haemorrhagic stroke
    • CNS tumour
    • Drugs - levodopa, antiepileptics, antipsychotics, stimulants, benzodiazepines, OCP, lithium
    • Infectious - Sydenham’s chorea (rheumatic fever), herpes simplex encephalitis, HIV, prions
    • Metabolic - pregnancy, thyrotoxicosis
    • Autoimmune - SLE, anti-phospholipid syndrome, scleroderma
  • The term chorea derives from the Greek koreia, ‘dance'.
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