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Haem History
 
 

Drugs: Thrombotic Microangiopathy

February 15th, 2021
 
 
 
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Overview

  • Causes of Drug-Induced Thrombotic Microangiopathic Anaemias

  • Acute Immune Reactions

  • Antiplatelets - clopidogrel, ticlodipine
  • Quinine
  • Cocaine
  • Toxic

  • Chemotherapy - mitomycin, cisplatin, oxaliplatin, gemcitabine, vincristine
  • Immunotherapy - interferons, bevacizumab
  • Immunosuppressants - cyclosporine, tacrolimus, sirolimus
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