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Upper Limb Neuro

Mononeuritis Multiplex

February 15th, 2021


Mononeuritis multiplex (also known as mononeuropathy multiplex and multiple mononeuropathy) is a peripheral neuropathy that affects two or more peripheral nerves.
  • Signs of Mononeuritis Multiplex

  • Lower motor neuron weakness affecting two or more distinct peripheral nerve distributions
  • Sensory loss affecting two or more distinct peripheral nerve distributions
  • Causes of Mononeuritis Multiplex

  • Vasculitis - polyarteritis nodosa, EGPA, GPA, cryoglobulinaemia, SLE, rheumatoid arthritis, Sjogren's syndrome, scleroderma, Behcet's disease
  • Diabetes
  • Infection - Lyme disease, leprosy, HIV, hepatitis B / C
  • Malignancy - lymphoma, small cell lung cancer
  • Amyloidosis
  • Sarcoidosis
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