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Upper Limb Neuro

Distal Weakness

February 15th, 2021


Distal weakness is more commonly a manifestation of neuropathy, though may also occur in certain muscular conditions.
  • Signs of Distal Weakness

  • Wasting of the small muscles of the hand
  • Foot drop
  • Distal weakness - particularly affecting the hands, wrists and ankles
  • Distal functional impairment - difficulty opening jars, turning a key, buttoning a shirt
  • Causes of Distal Weakness

  • Unilateral

  • Radiculopathy (C8/T1)
  • Brachial plexopathy
  • Peripheral nerve lesion
  • Bilateral

  • Guillain-Barre syndrome
  • Chronic inflammatory demyelinating polyneuropathy
  • Multifocal motor neuropathy with conduction block
  • Motor neurone disease
  • Inclusion body myositis
  • Myotonic dystrophy
  • Congenital distal myopathies
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