Cutaneous Manifestations of Neurologic Disease
Signs of Neurofibromatosis Type 1 (NF1)
- Neurofibromata: non-painful rubbery skin tumours
- Cafe au Lait spots: flat (macular) patches of hyperpigmentation
Signs of Tuberous Sclerosis Complex (TSC)
- Angiofibromata: pink papules in the nasolabial folds
- Shagreen patches: soft flesh-coloured patches on the trunk
- Ash leaf macules: hypopigmented flat spots
Signs of Meningitis
- Purpura: non-blanching red / purple lesions
- Maculopapular rash: blanching flat (macular) and raised (papular) lesions
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