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Hand & Wrist Exam


July 7th, 2019
On this page:Pathogenesis


  • Signs of Gout

  • Active monoarthritis - particularly of the first MTP joint (podagra) or tarsal joint
  • Asymmetric polyarthritis
  • Gouty tophi - particularly over joints; the olecranon bursa at the elbow; the helix of the ear; the infrapatellar and achilles tendons
  • X-Ray Findings in Gout

  • Soft tissue swelling
  • Joint space preservation (no joint space narrowing)
  • Tophi - periarticular radiolucent masses
  • Juxta-articular 'punched-out' erosions
  • Joint destruction (late)


  • Risk Factors for Gout

  • Male gender
  • Obesity
  • Chronic kidney disease
  • Drugs - diuretics, ethambutol, certain chemotherapeutic agents
  • Excess purine-rich foods - beer, shellfish, liver, marmite
  • Excess sucrose / fructose intake
  • Alcohol excess
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