- Mechanism of Action
- Selectively agonises serotonin 5-HT1 receptors, mainly found in cerebral and dural blood vessels.
Clinical Use
- Indication
- Second-line therapy for acute migraine.
- Contraindications
- Ischaemic heart disease, or high risk of IHD
- Cerebrovascular disease
- Peripheral vascular disease
- Uncontrolled hypertension
- Adverse Effects
- Drowsiness
- Dizziness
- Paraesthesia
- Weakness
- Chest tightness
- Nausea / vomiting
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