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Drug Guide
 
 

Vincristine

 
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    IV
    Vincristine
    Oncovin 
  • Mechanism of Action

  • Inhibits cell proliferation by preventing polymerization of tubulin into microtubules.

Clinical Use

  • Indications

  • Certain solid organ and haematologic malignancies, as guided by cancer specialists and local guidelines.
  • Adverse Effects
  • Neurotoxicity – numbness / paraesthesia / weakness
  • Leukopaenia / anaemia / thrombocytopaenia
  • Nausea / vomiting / constipation / paralytic ileus
  • Alopecia
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